Impromidine

Impromidine
Clinical data
ATC code	none;
Identifiers
	IUPAC name 2-[3-(1H-imidazol-5-yl)propyl]-1-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine;
CAS Number	55273-05-7 ;
PubChem CID	41376;
IUPHAR/BPS	1226;
ChemSpider	37757 ;
UNII	931L4X5WMM;
ChEMBL	ChEMBL12608 ;
CompTox Dashboard (EPA)	DTXSID90203780 ;
Chemical and physical data
Formula	C14H23N7S
Molar mass	321.45 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Cc1[nH]cnc1CSCCNC(=N)NCCCc2c[nH]cn2;
	InChI InChI=1S/C14H23N7S/c1-11-13(21-10-19-11)8-22-6-5-18-14(15)17-4-2-3-12-7-16-9-20-12/h7,9-10H,2-6,8H2,1H3,(H,16,20)(H,19,21)(H3,15,17,18) ; Key:MURRAGMMNAYLNA-UHFFFAOYSA-N ;
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Impromidine (INN) is a highly potent and specific histamine H₂ receptor agonist.^[1]

It has been used diagnostically as a gastric secretion indicator.

References

^ Durant G, Duncan W, Ganellin C, Parsons M, Blakemore R, Rasmussen A (1978). "Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors". Nature. 276 (5686): 403–5. doi:10.1038/276403a0. PMID 714166. S2CID 4242863.