Ronifibrate

Ronifibrate
Clinical data
Other names3-[(pyridin-3-yl)carbonyloxy]propyl 2-(4-chlorophenoxy)-2-methylpropanoate
ATC code
Identifiers
IUPAC name
  • 3-{[2-(4-chlorophenoxy)-2-methylpropanoyl]oxy}propyl nicotinate
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H20ClNO5
Molar mass377.82 g·mol−1
3D model (JSmol)
SMILES
  • O=C(OCCCOC(=O)C(Oc1ccc(Cl)cc1)(C)C)c2cccnc2
InChI
  • InChI=1S/C19H20ClNO5/c1-19(2,26-16-8-6-15(20)7-9-16)18(23)25-12-4-11-24-17(22)14-5-3-10-21-13-14/h3,5-10,13H,4,11-12H2,1-2H3 checkY
  • Key:AYJVGKWCGIYEAK-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Ronifibrate is a fibrate, a hypolipidemic agent. It is a combined ester of clofibric acid and niacin (nicotinic acid) with 1,3-propanediol. In the body, the ester is split to 1,3-propanediol and both acids which work in the same way, lowering lipids in blood.

References



This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.