You can specify the maximum amount of physical memory dedicated to the MemoryCache in the application config file using the namedCaches element, or by passing in the setting when you create your MemoryCache instance via the NameValueCollection passed into the constructor by putting an entry in the collection with a key of cacheMemoryLimitMegabytes and a value of 10.
Here is an example of the namedCaches configuration element:
<configuration>
<system.runtime.caching>
<memoryCache>
<namedCaches>
<add name="Default"
cacheMemoryLimitMegabytes="10"
physicalMemoryLimitPercentage="0"
pollingInterval="00:05:00" />
</namedCaches>
</memoryCache>
</system.runtime.caching>
</configuration>
And here is how you can configure the MemoryCache during creation:
//Create a name / value pair for properties
var config = new NameValueCollection();
config.Add("pollingInterval", "00:05:00");
config.Add("physicalMemoryLimitPercentage", "0");
config.Add("cacheMemoryLimitMegabytes", "10");
//instantiate cache
var cache = new MemoryCache("CustomCache", config);
This blog post details just about all of the ways to configure the MemoryCache object, and some examples were adapted from this source.