Valproate pivoxil |
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Routes of administration | Oral |
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| ATC code | |
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| Legal status |
- In general: ℞ (Prescription only)
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[(2,2-dimethylpropanoyl)oxy]methyl 2-propylpentanoate
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| CAS Number | |
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| PubChem CID | |
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| ChemSpider | |
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| UNII | |
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| CompTox Dashboard (EPA) | |
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| ECHA InfoCard | 100.071.502 |
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| Formula | C14H26O4 |
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| Molar mass | 258.358 g·mol−1 |
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| 3D model (JSmol) | |
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O=C(OCOC(=O)C(C)(C)C)C(CCC)CCC
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InChI=1S/C14H26O4/c1-6-8-11(9-7-2)12(15)17-10-18-13(16)14(3,4)5/h11H,6-10H2,1-5H3 YKey:DJEFRLDEQKSNLM-UHFFFAOYSA-N Y
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N Y (what is this?) (verify) |
Valproate pivoxil (Pivadin, Valproxen) is an anticonvulsant used in the treatment of epilepsy.[1] It is the pivaloyloxymethyl ester derivative of valproic acid.[2] It is likely a prodrug of valproic acid, as pivoxil esters are commonly employed to make prodrugs in medicinal chemistry.
See also
References
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| Transporter | | GATTooltip GABA transporter | |
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| VIAATTooltip Vesicular inhibitory amino acid transporter | |
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| Enzyme | | GADTooltip Glutamate decarboxylase |
- Inhibitors: 3-Mercaptopropionic acid
- AAOA
- L-Allylglycine
- Semicarbazide
- Activators: 3-Methyl-GABA
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| GABA-TTooltip γ-Aminobutyrate aminotransferase |
- Activators: 3-Methyl-GABA
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| Other | |
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- See also
- Receptor/signaling modulators
- GABA receptor modulators
- GABAA receptor positive modulators
- Glutamate metabolism/transport modulators
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See also: Receptor/signaling modulators |
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| Calcium | | VDCCsTooltip Voltage-dependent calcium channels | |
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| Potassium | | VGKCsTooltip Voltage-gated potassium channels | |
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| IRKsTooltip Inwardly rectifying potassium channel | | Blockers | |
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| Activators |
- GIRKTooltip G protein-coupled inwardly rectifying potassium channel-specific: ML-297 (VU0456810)
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| KCaTooltip Calcium-activated potassium channel | |
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| K2PsTooltip Tandem pore domain potassium channel | |
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| Sodium | | VGSCsTooltip Voltage-gated sodium channels | |
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| ENaCTooltip Epithelial sodium channel | |
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| ASICsTooltip Acid-sensing ion channel | |
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| Chloride | | CaCCsTooltip Calcium-activated chloride channel | |
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| CFTRTooltip Cystic fibrosis transmembrane conductance regulator | |
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| Unsorted | |
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| Others | | TRPsTooltip Transient receptor potential channels | |
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| LGICsTooltip Ligand gated ion channels | |
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See also: Receptor/signaling modulators • Transient receptor potential channel modulators |