Real-time outbreak and disease surveillance system (RODS) is a syndromic surveillance system developed by the University of Pittsburgh, Department of Biomedical Informatics.[1] It is "prototype developed at the University of Pittsburgh where real-time clinical data from emergency departments within a geographic region can be integrated to provide an instantaneous picture of symptom patterns and early detection of epidemic events."[2]
RODS uses a combination of various monitoring tools.[3]
- The first tool is a moving average with a 120-day sliding phase-I-window.
- The second tool is a nonstandard combination of CUSUM and EWMA, where an EWMA is used to predict next-day counts, and a CuSum monitors the residuals from these predictions.
- The third monitoring tool in RODS is a recursive least squares (RLS) algorithm, which fits an autoregressive model to the counts and updates estimates continuously by minimizing prediction error. A Shewhart I-chart is then applied to the residuals, using a threshold of 4 standard deviations.
- The fourth tool in RODS implements a wavelet approach, which decomposes the time series using Haar wavelets, and uses the lowest resolution to remove long-term trends from the raw series. The residuals are then monitored using an ordinary Shewhart I-chart with a threshold of 4 standard deviations.
References
- ^ RODS Laboratory Website
- ^ Public Health-Related Activities at the
US HHS government website. Accessed December 2, 2010.
- ^ Shmueli, G., Burkom, H.S., "Statistical Challenges Facing Early Outbreak Detection in Biosurveillance", Technometrics (Special Issue on Anomaly Detection), vol. 52, issue 1, pp. 39–51, 2010
United States biological defense program |
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| Organizations | Federal administrative | | DHS |
- DHS Chemical and Biological Defense Division
- DHS Office of Health Affairs (National Biosurvelliance Integration Center, BioWatch)
- National Biodefense Analysis and Countermeasures Center
- National Bio and Agro-Defense Facility
- National Bioforensic Analysis Center
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| DNI |
- National Counterproliferation Center (Advisory Committee on Bioterrorism)
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| DHHS | |
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| DoD |
- Assistant SECDEF for NCB Defense Programs
- Defense Threat Reduction Agency
- Global Emerging Infections Surveillance and Response System
- Joint Program Executive Office of Chemical and Biological Defense (JPEO-CBD)
- National Center for Medical Intelligence
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Federal research | Trans- departmental | |
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| Military |
- U.S. Army Medical Research Institute of Infectious Diseases
- Defense Advanced Research Projects Agency
- Edgewood Chemical Biological Center
- Dugway Proving Ground
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| Civilian | |
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| Response | |
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Non- governmental | Academic centers and think tanks |
- Johns Hopkins Center for Health Security (formerly Center for Biosecurity)
- Henry L. Stimson Center
- Center for Advancing Microbial Risk Assessment
- Center for Biodefense and Emerging Pathogens (Brown University)
- Middle-Atlantic Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research
- Center for Biodefense Immune Modeling (University of Rochester)
- Johns Hopkins Center for Civilian Biodefense Strategies
- National Center for Biodefense and Infectious Diseases (NCBID; George Mason Univ.)
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Government contractors |
- Battelle Memorial Institute
- SRI International
- Idaho Technology
- Phoenix Air
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Programs and projects | | Threat reduction |
- Nunn–Lugar Cooperative Threat Reduction Program, implemented the Defense Threat Reduction Agency and Biological Threat Reduction (DoD) plus
- Project Bacchus
- Project Clear Vision
- Project Jefferson
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| Biosurveillance | |
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| Biosecurity/Biosurety | |
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| Medical intelligence | |
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| Disaster response |
- National Response Framework of the National Strategy for Homeland Security (DHS; including NIMS and ICS)
- National Disaster Medical System (DHHS)
- Strategic National Stockpile (CDC, DHS)
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Technology and equipment | | Protection | |
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| Detection |
- Cell CANARY
- Biological Materials MASINT
- Autonomous Pathogen Detection System
- Joint Biological Agent Identification and Diagnostic System (JBAIDS)
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| Biocontainment | |
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| Law | | Treaties |
- Geneva Protocol (1925, 1975)
- Statement on Chemical and Biological Defense Policies and Programs (1969)
- Biological Weapons Convention (1972)
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| Legislation | |
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International representation |
- Global Health Security Initiative
- Global Partnership Against the Spread of Weapons and Materials of Mass Destruction
- United Nations Security Council Resolution 1540 (2004)
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| History | Past biological incidents | |
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Defunct organizations and programs |
- United States Army Medical Unit
- United States biological weapons program
- Sunshine Project
- Aeromedical Isolation Team (DoD)
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| Related topics |
- Agro-terrorism
- Biodefense
- Biosecurity in the United States
- Biological agent
- Biological hazard
- Biological warfare (BW)
- Biosurveillance
- Bioterrorism
- CBRN defense
- Decontamination
- Entomological warfare
- Isolation (health care)
- Select agent
- Smallpox virus retention debate
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